Achieving high-quality development is an essential requirement of Chinese modernization, and coordinated regional development is an inherent requirement of high-quality development. Against the background of comprehensive rule of law, promoting high-quality development must be run on the track of modernization of Chinese-style rule of law, and regional economic rule of law is the legal response to coordinated regional high-quality development. Regional economic rule of law is based on a mixed governance structure of hard and soft law, including regional economic enacted law and regional economic soft law, which can promote value justice, institution justice, production justice, and distribution justice in the development space, thereby ensuring the realization of overall spatial justice in coordinated regional high-quality development. From the practice of regional economic rule of law, there are still four kinds of problems: problems such as imperfection of regional economic enacted law, imperfection of coordinated regional legislation mechanisms, and incongruity between regional economic policies and legislation at the legislation level; problems such as imperfection of regional enforcement rules, and lack of coordination in enforcement mechanisms at the law-enforcement level; problems such as shallow degree of judicial coordination, and slow construction of specialized courts across administrative divisions at the judicial level; problems such as insufficient promotion and innovation systems for regional economic rule of law, and inadequate construction of regional compliance evaluation mechanisms at the compliance level. These problems prevent the effective play of the function of regional economic rule of law. Based on the framework of “rule-mechanism”, we need to accelerate the formulation of regional economic basic law, improve coordinated regional legislation mechanisms, and realize the horizontal and vertical coordination of regional economic legislation; improve the “central-local” regional economic law-enforcement rules, strengthen regional law-enforcement coordination mechanisms, and promote the normalization of regional economic law-enforcement coordination; improve the system of “procedure-organization” regional economic justice rules, deepen regional judicial coordination mechanisms, and promote the coordination and integration of regional economic justice resources; and improve the rule system and collaborative cultivation mechanism for the construction of regional economic rule of law culture, and promote the cultivation of regional economic rule of law concepts. In this way, high-quality regional economic rule of law is used to promote coordinated regional high-quality development.